ARG1-IN-1

ARG1-IN-1

• CAS Number: 2376189-62-5
• UNSPSC Description: ARG1-IN-1 (example 1) is a human arginase 1 inhibitor with an IC50 of 29 nM[1].
• Target Antigen: Arginase
• Type: Reference compound
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/arg1-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: OB(O)CCC[C@H]1[C@@]2([H])[C@@](CNC2)([H])C[C@@]1(N)C(O)=O
• Molecular Weight: 256.11
• References & Citations: [1]Mitcheltree MJ, et al. Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy. ACS Med Chem Lett. 2020 Mar 23;11(4):582-588.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported