Borocaptate (sodium)

• Description :

  Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity[1][2].

• Product Name Alternative :

  BSH

• UNSPSC :

  12352300

• Hazard Statement :

  H315, H319, H335

• Target :

  Biochemical Assay Reagents

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/borocaptate-sodium.html

• Purity :

  95.0

• Solubility :

  H2O : 175 mg/mL (ultrasonic)

• Smiles :

  SB1234c567c89%10c%11%12%13c581C%11%142c%15%163c%12%17%14c%13%189c6%19%10c%1574c%17%16%18%19.C[BH].[2Na+].[2-]

• Molecular Formula :

  B12H12Na2S

• Molecular Weight :

  219.87

• Precautions :

  H315, H319, H335

• References & Citations :

  [1]Bendel P, et al. Optimal detection of the neutron capture therapy agent borocaptate sodium (BSH) : A comparison between and NMR[J]. Medical Physics, 2001, 28 (2) : 178-183.|[2]Kraft SL, et al. Borocaptate sodium: a potential boron delivery compound for boron neutron capture therapy evaluated in dogs with spontaneous intracranial tumors. Proc Natl Acad Sci U S A. 1992 Dec 15;89 (24) :11973-7.|[3]Yoshida F, et al. Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect. Cancer Lett. 2004 Nov 8;215 (1) :61-7.|[4]Kokai-Kun J F, et al. Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model[J]. Journal of antimicrobial chemotherapy, 2007, 60 (5) : 1051-1059.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, stored under nitrogen, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [144885-51-8]