F594-1001
CAT:
804-HY-160943
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
F594-1001
- CAS Number: 1215326-44-5
- UNSPSC Description: F594-1001 (compound 6) is a potent and highly selective SARS-CoV-2 Mac1-ADP-ribose inhibitor with IC50s of 8.5 μM, 68 μM and 45 μM for SARS-CoV-2 in AS, FP, and FRET assays, respectively. F594-1001 directly binds to SARS-CoV-2 Mac1 and exhibits a dose-dependent inhibition of Mac1 ADP-ribosylhydrolase activity[1].
- Target Antigen: SARS-CoV
- Type: Reference compound
- Related Pathways: Anti-infection
- Applications: COVID-19-anti-virus
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/f594-1001.html
- Smiles: O=C(N(CCC(N1CCNCC1)=O)CC2=CC(Cl)=CC=C2)C3=CC(OC)=CC(OC)=C3
- Molecular Weight: 445.94
- References & Citations: [1]Anu Roy, et al. Discovery of compounds that inhibit SARS-CoV-2 Mac1-ADP-ribose binding by high-throughput screening. Antiviral Res. 2022 Jul:203:105344.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported