P2X7-IN-2 (TFA)
CAT:
804-HY-18725A-04
Size:
25 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
P2X7-IN-2 (TFA)
- UNSPSC Description: P2X7-IN-2 TFA (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 TFA inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 TFA can be used for the research of autoimmunity, inflammation and cardiovascular disease[1].
- Target Antigen: Interleukin Related; P2X Receptor
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;Membrane Transporter/Ion Channel
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/p2x7-in-2-tfa.html
- Purity: 99.93
- Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(NC1=C(C)C=CC2=C1C=CN([C@H](C)CN)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3.O=C(O)C(F)(F)F
- Molecular Weight: 549.44
- References & Citations: [1]Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
- Clinical Information: No Development Reported