P2X7-IN-2
CAT:
804-HY-18725
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
P2X7-IN-2
- CAS Number: 1058709-63-9
- UNSPSC Description: P2X7-IN-2 (compound 58) is a P2X7 receptor inhibitor. P2X7-IN-2 inhibits IL-Iβ release with an IC50 value of 0.01 nM. P2X7-IN-2 can be used for the research of autoimmunity, inflammation and cardiovascular disease[1].
- Target Antigen: Interleukin Related; P2X Receptor
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;Membrane Transporter/Ion Channel
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology; Cardiovascular Disease
- Assay Protocol: https://www.medchemexpress.com/p2x7-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=C(C)C=CC2=C1C=CN([C@H](C)CN)C2=O)CC3=CC=C(C(F)(F)F)C(F)=C3
- Molecular Weight: 435.41
- References & Citations: [1]Kelly, Michael G, et al. Preparation of isoquinolonecarboxamides as P2X7 purinoceptor modulators and uses thereof. WO2008112205 A1. 2008.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported