Hexadecanamide

• Product Name Alternative:

  Palmitamide

• UNSPSC Description:

  Hexadecanamide (Palmitamide), a fatty acid amide, has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide alleviate S. aureus-caused mastitis by depressing inflammatory response and maintaining blood-milk barrier integrity. Hexadecanamide depresses S. aureus-induced activation of the NF-κB pathway in mouse mammary epithelial cells (MMECs). Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro[1][2].

• Target Antigen:

  Bacterial; NF-κB; PPAR

• Type:

  Natural Products

• Related Pathways:

  Anti-infection;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease;NF-κB;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/hexadecanamide.html

• Purity:

  97.0

• Solubility:

  DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  NC(CCCCCCCCCCCCCCC)=O

• Molecular Weight:

  255.44

• References & Citations:

  [1]Bao L, et al. Hexadecanamide alleviates Staphylococcus aureus-induced mastitis in mice by inhibiting inflammatory responses and restoring blood-milk barrier integrity. PLoS Pathog. 2023 Nov 10;19(11):e1011764.|[2]Han B, et al. Changes in seminal plasma microecological dynamics and the mechanistic impact of core metabolite hexadecanamide in asthenozoospermia patients. Imeta. 2024 Jan 25;3(2):e166. https://pubmed.ncbi.nlm.nih.gov/38882497/

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  Store at room temperature 3 years

• Clinical Information:

  No Development Reported

• CAS Number:

  629-54-9