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Hexadecanamide

CAT: 0804-HY-121389-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-121389-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Hexadecanamide (Palmitamide) is a fatty acid amide that has orally active anti-allergic, antioxidant, and neuroprotective effects. Hexadecanamide exerts protective effects in Staphylococcus aureus- and SARA-induced mastitis. Hexadecanamide suppresses S. aureus-induced activation of the NF-κB pathway and improves blood-milk barrier integrity. Hexadecanamide activates PPARα. Hexadecanamide enhances sperm motility in vitro. Hexadecanamide can be studied in research for mastitis and asthenozoospermia[1][2].
CAS Number
629-54-9
Product Name Alternative
Palmitamide
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; NF-κB; PPAR
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hexadecanamide.html
Purity
97.0
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
NC(CCCCCCCCCCCCCCC)=O
Molecular Formula
C16H33NO
Molecular Weight
255.44
Precautions
H302, H315, H319, H335
References & Citations
[1]Bao L, et al. Hexadecanamide alleviates Staphylococcus aureus-induced mastitis in mice by inhibiting inflammatory responses and restoring blood-milk barrier integrity. PLoS Pathog. 2023 Nov 10;19 (11) :e1011764.|[2]Han B, et al. Changes in seminal plasma microecological dynamics and the mechanistic impact of core metabolite hexadecanamide in asthenozoospermia patients. Imeta. 2024 Jan 25;3 (2) :e166. https://pubmed.ncbi.nlm.nih.gov/38882497/
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
PPARα

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