TBK1/IKKε-IN-2

• UNSPSC Description:

  TBK1/IKKε-IN-2 is a dual TBK1 and IKKε inhibitor.

• Target Antigen:

  IKK

• Type:

  Reference compound

• Related Pathways:

  NF-κB

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/IKK_epsilon_-IN-1.html

• Purity:

  98.09

• Solubility:

  DMSO : 21.5 mg/mL (ultrasonic;warming)

• Smiles:

  N#CC1=CC(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)=CC=C1OC5CCOCC5

• Molecular Weight:

  457.52

• References & Citations:

  [1]Muvaffak A, et al. Evaluating TBK1 as a therapeutic target in cancers with activated IRF3. Mol Cancer Res. 2014 Jul;12(7):1055-66.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1292310-49-6