Kansuinine E

• Description :

  Kansuinine E is a plant-derived nitric oxide inhibitor (IC50=6.3 μM) . Kansuinine E belongs to jatrophane-type diterpenoids and is isolated from the roots of E. kansui[1].

• UNSPSC :

  12352005

• Target :

  NO Synthase

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/kansuinine-e.html

• Solubility :

  10 mM in DMSO

• Smiles :

  C[C@H]1C[C@@]2(OC(C)=O)[C@@H]([C@@H](OC(C)=O)C([C@H](OC(C)=O)[C@@H](OC(C3=CC=CC=C3)=O)[C@@H](OC(C4=CN=CC=C4)=O)C(C)(C)[C@@H]5[C@H]([C@@H](C)C2=O)O5)=C)[C@H]1OC(C)=O

• Molecular Formula :

  C41H47NO14

• Molecular Weight :

  777.81

• References & Citations :

  [1]Lee JW, et al. Jatrophane and ingenane-type diterpenoids from Euphorbia kansui inhibit the LPS-induced NO production in RAW 264.7 cells. Bioorg Med Chem Lett. 2016;26 (14) :3351-3354.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [672945-84-5]