MLS-0437605

• UNSPSC Description:

  MLS-0437605 is a selective dual-specificity phosphatase 3 (DUSP3) inhibitor with an IC50 of 3.7 μM. MLS-0437605 is more selective for DUSP3 than DUSP22 and other protein tyrosine phosphatases (PTPs)[1].

• Target Antigen:

  Phosphatase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/mls-0437605.html

• Purity:

  99.92

• Solubility:

  DMSO : ≥ 20.83 mg/mL

• Smiles:

  COC1=CC=C(C2=NN=C(NC3=NC4=C(F)C=CC=C4S3)O2)C=C1

• Molecular Weight:

  342.35

• References & Citations:

  [1]Lucia Musumeci, et al. Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis. Circulation. 2015 Feb 17;131(7):656-68.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  862975-18-6