DMS-612

• Description:

  DMS-612 (NSC-281612) is an alkylating agent with anti-renal cell carcinoma activity. DMS-612 can be used in cancer research[1].

• Product Name Alternative:

  NSC-281612

• UNSPSC:

  12352005

• Target:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/dms-612.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=CC1=CC=C(N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)C=C1C

• Molecular Formula:

  C14H21NO7S2

• Molecular Weight:

  379.45

• References & Citations:

  [1]Parise RA, et al. Formation of active products of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) in human blood and plasma and their activity against renal cell carcinoma lines. Cancer Chemother Pharmacol. 2013 Jan;71 (1) :73-83. doi: 10.1007/s00280-012-1980-1. Epub 2012 Oct 5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [56967-08-9]