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A-437203

CAT: 0804-HY-U00185-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-U00185-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A-437203 is a selective D3 receptor antagonist with Ki of 71, 1.6, and 6220 nM for D2, D3, and D4 receptors, respectively.
CAS Number
220519-06-2
Product Name Alternative
Lu201640; A37203
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/A37203.html
Purity
99.08
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C1NC(SCCCN2CCN(C3=NC(C(C)(C)C)=NC(C(F)(F)F)=C3)CC2)=NC=C1
Molecular Formula
C20H27F3N6OS
Molecular Weight
456.53
References & Citations
[1]Basso AM, et al. Antidepressant-like effect of D (2/3) receptor-, but not D (4) receptor-activation in the rat forced swim test. Neuropsychopharmacology. 2005 Jul;30 (7) :1257-68.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
D3 Receptor

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