Thapsigargin

• Description :

  Thapsigargin, an endoplasmic reticulum (ER) stress inducer, is an inhibitor of microsomal Ca2+-ATPase. Thapsigargin efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication in different cell types[1][2][3][4][5].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H334, H335

• Target :

  Apoptosis; Calcium Channel; SARS-CoV

• Type :

  Natural Products

• Related Pathways :

  Anti-infection; Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/Thapsigargin.html

• Purity :

  99.95

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  CCCCCCCC(O[C@@H]1[C@@H](OC(/C(C)=C\C)=O)C(C)=C2[C@@]1([H])[C@@](C)(OC(C)=O)C[C@H](OC(CCC)=O)[C@@]([C@@]3(O)C)(O)[C@@]2([H])OC3=O)=O

• Molecular Formula :

  C34H50O12

• Molecular Weight :

  650.75

• Precautions :

  H315, H319, H334, H335

• References & Citations :

  2+

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [67526-95-8]