Captopril EP Impurity C

• Description :

  Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) [1][2][3].

• Product Name Alternative :

  3-Mercaptoisobutyric acid

• UNSPSC :

  12352211

• Hazard Statement :

  H290-H301-H314-H332-H402

• Target :

  Drug Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/captopril-ep-impurity-c.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)C(C)CS

• Molecular Formula :

  C4H8O2S

• Molecular Weight :

  120.17

• Precautions :

  P234-P260-P261-P264-P270-P271-P273-P280-P301+P330+P331-P304+P340-P330-P363-P390-P405-P406-P501

• References & Citations :

  [1]ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL.|[2]Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64 (11) :2263-2268.|[3]Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [26473-47-2]