Captopril EP Impurity C

CAT: 0804-HY-137769-01Size: 50 mgDry Ice: NoHazardous: No
CAT#:0804-HY-137769-01Size:50 mg
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Description
Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) [1][2][3].
CAS Number
[26473-47-2]
Product Name Alternative
3-Mercaptoisobutyric acid
UNSPSC
12352211
Hazard Statement
H290-H301-H314-H332-H402
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/captopril-ep-impurity-c.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(C)CS
Molecular Formula
C4H8O2S
Molecular Weight
120.17
Precautions
P234-P260-P261-P264-P270-P271-P273-P280-P301+P330+P331-P304+P340-P330-P363-P390-P405-P406-P501
References & Citations
[1]ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL.|[2]Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64 (11) :2263-2268.|[3]Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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