Captopril EP Impurity D

CAT: 0804-HY-W015332-01Size: 1 gDry Ice: NoHazardous: No
CAT#:0804-HY-W015332-01Size:1 g
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Description
Captopril EP Impurity D is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM) [1][2][3].
CAS Number
[56970-78-6]
Product Name Alternative
3-Bromoisobutyric acid
UNSPSC
12352211
Hazard Statement
H290, H302, H314, H332, H341
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/captopril-ep-impurity-d.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C(C)CBr
Molecular Formula
C4H7BrO2
Molecular Weight
167.00
Precautions
H290, H302, H314, H332, H341
References & Citations
[1]ANCA GABRIELA CÂRJE, et al. HPLC-UV METHOD APPROACH FOR THE ANALYSIS AND IMPURITY PROFILING OF CAPTOPRIL.|[2]Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64 (11) :2263-2268.|[3]Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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