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GSK334429

CAT: 0804-HY-116386Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116386Size:1 Each
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Description
GSK334429 is a selective and orally active non-imidazole histamine H3 receptor antagonist with a pKi of 9.49 against human H3 receptor. GSK334429 can be utilized in neurological research[1].
CAS Number
799557-57-6
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gsk334429.html
Smiles
O=C(N1CCN(C(C)C)CCC1)C2CCN(C3=CC=C(C(F)(F)F)N=C3)CC2
Molecular Formula
C20H29F3N4O
Molecular Weight
398.47
References & Citations
[1]Medhurst AD, et al. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats. Biochem Pharmacol. 2007 Apr 15;73 (8) :1182-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H3 Receptor

Alternative Products

CatalogName
T27473-01GSK334429
ZGB55894-01GSK334429 hydrochloride

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