Bispyribac (sodium)

• Description:

  Bispyribac sodium is a selective, orally active, systemic and post-emergence herbicide. Bispyribac sodium reduces SOD levels and inhibits ALS activity. Bispyribac sodium blocks the biosynthesis of branched-chain amino acids, resulting in growth retardation, chlorosis and necrosis of weeds. Bispyribac sodium exerts herbicidal activity against grass, sedge and broadleaf weeds in rice fields. Bispyribac sodium is hepatotoxic and genotoxic[1][2][3][4].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Acetolactate Synthase (ALS) ; SOD

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/bispyribac-sodium.html

• Purity:

  99.56

• Solubility:

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  O=C(O[Na])C1=C(OC2=NC(OC)=CC(OC)=N2)C=CC=C1OC3=NC(OC)=CC(OC)=N3

• Molecular Formula:

  C19H17N4NaO8

• Molecular Weight:

  452.35

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Ahmad F, Anwar S, Firdous S, Da-Chuan Y, Iqbal S. Biodegradation of bispyribac sodium by a novel bacterial consortium BDAM: Optimization of degradation conditions using response surface methodology. J Hazard Mater. 2018;349:272-281.|[2]Osuna M D, et al. Cross-resistance to bispyribac-sodium and bensulfuron-methyl in Echinochloa phyllopogon and Cyperus difformis. Pesticide Biochemistry and Physiology, 2002, 73 (1) : 9-17.|[3]Sleem R F, et al. Genotoxicity of bispyribac sodium in albino rats. Mansoura Veterinary Medical Journal, 2017, 18 (1) : 491-502.|[4]Nasir A S, et al. Bispyribac Sodium Induced Oxidative Stress and Hepatotoxicity in the Female Rats. Annals of the Romanian Society for Cell Biology, 2021, 25 (7) : 273-283.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [125401-92-5]