Gondoic acid

• Description :

  Gondoic acid (cis-11-Eicosenoic acid), a monounsaturated long-chain fatty acid, is contained in a variety of plant oils and nuts. Gondoic acid can exert anti-inflammatory activity by inhibiting the production of ROS and the PKCθ/ERK/STAT3 signaling pathway. Gondoic acid can be used as a raw material for medical supplies and a moisturizing ingredient in cosmetic creams[1][2].

• Product Name Alternative :

  Cis-11-Eicosenoic acid

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite; ERK; PKC; Reactive Oxygen Species (ROS) ; STAT

• Type :

  Natural Products

• Related Pathways :

  Epigenetics; Immunology/Inflammation; JAK/STAT Signaling; MAPK/ERK Pathway; Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt; TGF-beta/Smad

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/gondoic-acid.html

• Concentration :

  10mM

• Purity :

  98.0

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CCCCCCCC/C=C\CCCCCCCCCC(O)=O

• Molecular Formula :

  C20H38O2

• Molecular Weight :

  310.51

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]H Kikukawa, et al. Production of cis-11-eicosenoic acid by Mortierella fungi. J Appl Microbiol. 2015 Mar;118 (3) :641-7.|[2]Fan G, et al. Gondoic acid alleviates LPS‑induced Kupffer cells inflammation by inhibiting ROS production and PKCθ/ERK/STAT3 signaling pathway. Int Immunopharmacol. 2022 Oct;111:109171.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [5561-99-9]