Products for Research Use Only
RegisterLogin

Anti-BDNF Antibody

CAT: 1303-75-470Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1303-75-470Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Brain-derived neurotrophic factor is encoded by the gene BDNF and is a member of the neurotrophin family of growth factors. BDNF is a secreted signaling molecule with may important functions including axonal growth, modulation of dendritic growth, the promotion of survival/differentiation of neuronal populations in peripheral and central nervous systems, regulation of synaptic transmission/plasticity and long-term potentiation. BDNF is expressed highly in brain (in the hippocampus, amygdala, cerebral cortex and cerebellum) and expressed in lung, heart and skeletal muscle. Diseases associated with this gene include Congenital Central Hypoventilation Syndrome, Wilms Tumor, Aniridia and Mental Retardation Syndrome.
Description
Our Anti-BDNF mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N450/53. It detects mouse and rat BDNF, and is purified by Protein A chromatography. It is great for use in IHC, WB.
Short Description
Our Anti-BDNF mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N450/53. It detects mouse and rat BDNF, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.
Synonyms
Brain-derived neurotrophic factor (Abrineurin)
Gene Name
Bdnf
UniProt
P21237
Host
Mouse
Reactivity
Mouse and Rat
Immunogen
Fusion protein amino acids 1-249 (full length) of mouse BDNF (accession number P21237) produced recombinantly in E. Coli
Target
BDNF
Clonality
Monoclonal
Isotype
IgG2b
Clone
N450/53
Type
Primary Antibody
Applications
WB, IHC, ICC, ELISA
Field of Research
Neurogenesis and Development
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Molecular Weight
25-40 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity reported
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Mouse
WB Brain Quality Control
1
Conjugate
Unconjugated
RRID
AB_2722670

UniProtKB · P21237

Neurotrophic factor BDNF precursor form

BDNF_MOUSE · Mus musculus

View on UniProt ↗
Primary accession
P21237
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
Bdnf
Protein existence
1: Evidence at protein level
Organism
Mus musculus (Mouse)
Taxonomy ID
10090
Alternative names
proBDNF
EC number
—
Processing
Precursor
Secondary accessions
A2AII2, Q8CCH9
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoprotein

Technical term

Direct protein sequencingReference proteome

Molecular function

Growth factor

Cellular component

Secreted

Domain

Signal

Related Products

CatalogName
75-431Anti-VMAT1 Antibody
RP-4001-020Anti-Ferritin Antibody
77-522-020Anti-SARM1 Antibody
75-507Anti-GAD67 Antibody
75-502Anti-SAPAP3 Antibody
75-488Anti-Calretinin Antibody
75-482Anti-Collybistin Antibody
75-479Anti-Parvalbumin Antibody
75-468Anti-SAPAP1 Antibody
75-453Anti-Homer1L Antibody

Alternative Products

CatalogName
MBS7615591-01anti-BDNF antibody
STJ13100064Anti-mature BDNF antibody
STJ13100048Anti-pro BDNF antibody
dAP-2120Goat anti-BDNF Antibody
GTR18085338Anti-Bdnf

Popular Products