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Anti-PEX7 Antibody

CAT: 1303-75-256Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-256Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Peroxisomal Biogenesis Factor 7 is encoded by the gene PEX7. PEX7 is a member of the WD repeat peroxin-7 family. PEX7 binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. PEX7 is ubiquitously expressed with the highest levels in the pancreas, skeletal muscle, and heart. Diseases associated with PEX7 include Rhizomelic Chondrodysplasia Punctata, Type 1 and Peroxisome Biogenesis Disorder 9B.
Description
Our Anti-PEX7 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N232/9. It detects human PEX7, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Short Description
Our Anti-PEX7 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N232/9. It detects human PEX7, and is purified by protein a chromatography. It is great for use in WB, ICC, ELISA.
Synonyms
Peroxisomal targeting signal 2 receptor (PTS2 receptor) (Peroxin-7)
Gene Name
PEX7 PTS2R
UniProt
O00628
Host
Mouse
Reactivity
Human
Immunogen
Fusion protein amino acids 64-150 (WD1 and WD2 repeat domains) of human PEX7 (accession number O00628) produced recombinantly in E. Coli
Target
PEX7
Clonality
Monoclonal
Isotype
IgG2b
Clone
N232/9
Type
Primary Antibody
Applications
WB, ICC, ELISA
Field of Research
Rare Diseases
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Molecular Weight
40 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity reported
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Human
ICC Quality Control
1
Conjugate
Unconjugated
RRID
AB_10672985

UniProtKB · O00628

Peroxisomal targeting signal 2 receptor

PEX7_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00628
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PEX7
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
PTS2 receptor
EC number
—
Processing
—
Secondary accessions
C0H5X6
Protein keywords

Coding sequence diversity

Alternative splicing

Disease

CataractDeafnessDisease variantIchthyosisPeroxisome biogenesis disorderRetinitis pigmentosaRhizomelic chondrodysplasia punctata

Cellular component

CytoplasmPeroxisome

Biological process

Protein transportTransport

Technical term

Proteomics identificationReference proteome

Domain

RepeatWD repeat

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