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Anti-GIT2 Antibody

CAT: 1303-75-126Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-126Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G-protein coupled receptor kinase interacting ArfGAP 2 is encoded by the gene GIT2. GIT2 is a member of the GIT protein family. GIT2 has a be shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. GIT2 is expressed in 207 organs with the highest expression level in the right hemisphere of cerebellum. Diseases associated with GIT2 include Gastric Antral Vascular Ectasia and Systemic Scleroderma.
Description
Our Anti-GIT2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N83/48. It detects human, mouse, and rat GIT2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Short Description
Our Anti-GIT2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N83/48. It detects human, mouse, and rat GIT2, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.
Synonyms
ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2)
Gene Name
GIT2 KIAA0148
UniProt
Q14161
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Fusion protein amino acids 450-759 (C-terminus) of human GIT2 (accession number Q14161) produced recombinantly in E. Coli
Target
GIT2
Clonality
Monoclonal
Isotype
IgG1
Clone
N83/48
Type
Primary Antibody
Applications
WB, IHC, ICC, IP, ELISA
Field of Research
Scaffold Proteins
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.53
Molecular Weight
85 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity against GIT1
Quality Control
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Human
ICC Quality Control
1
Conjugate
Unconjugated
RRID
AB_2110013

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