Products for Research Use Only

Anti-Complement C4c Antibody

CAT: 1303-CAM 072-18-1Size: 1000 µLDry Ice: NoHazardous: No
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CAT#:1303-CAM 072-18-1Size:1000 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C4c is a compoment in the Complement cascade and is a degradation product of C4b which is cleaved by C4b/C3b inactivator to yield C4d and C4c (soluble) . C4c consists of a g-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa) . C4c reacts with C1 and C2 to form C3 convertase of the classic activation pathway.
Description
Our mouse Complement C4c monoclonal antibody from Antibodies Incorporated is produced in-house from clone 99-72-18. It detects human Complement C4c and is Protein A or Protein G purified. Works in ELISA, IF, IHC, IP, WB.
Synonyms
C4A, C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG, complement C4-A, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2, C4A anaphylatoxin, MHC class III region complement, Rodgers form of C4, acidic C4, acidic complement C4, complement C4A (Rodgers blood group), complement component 4A (Rodgers blood group)
Gene Name
C4A
NCBI Gene ID
720
UniProt
P0C0L4
Host
Mouse
Reactivity
Human
Immunogen
Synthetic peptide consisting of the last 15C-terminal residues of the C4c a4-domain (Cys-EELVYELNPLDHRGR) .`
Target
Complement C4c
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
99-72-18
Type
Primary Antibodies
Applications
ELISA, IF, IHC, IP, WB
Concentration
1 mg/mL ±15%
Format
Protein A or Protein G purified
Buffer
0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide
Molecular Weight
G-chain (30 kDa), a b-chain (75 kDa), and two a-domains denoted a3 (27 kDa) and a4 (14 kDa)
Shipping Conditions
Shipped on ice packs
Storage Conditions
2-8°C without exposure to light
Notes
BSA free
IHC Dilution
0.4583333333333333
Specificity
CAM 072-18 binds human complement factor C4c.
Brand
Antibodies Inc (via BioPorto acquisition)
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Human