YES1 Active Human

• Description:

  YES1 Active Human_x000D_ Catalog number: B2013749_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 ug_x000D_ Molecular Weight or Concentration: 91 kDa_x000D_ Supplied as: Solution_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: -20°C_x000D_ Keywords: HsT441, P61-YES, Yes, c-yes_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Redin E, Garrido-Martin EM, Valencia K, Redrado M, Solorzano JL, Carias R, Echepare M, Exposito F, Serrano D, Ferrer I, Nunez-Buiza A, Garmendia I, Garc_a-Pedrero JM, Gurpide A, Paz-Ares L, Politi K, Montuenga LM, Calvo A. YES1 Is a Druggable Oncogenic Target in SCLC J Thorac Oncol. 2022 Dec;17(12):1387-1403._x000D_ 2: Mao L, Yuan W, Cai K, Lai C, Huang C, Xu Y, Zhong S, Yang C, Wang R, Zeng P, Huang H, Chen Z, Chen Z. EphA2-YES1-ANXA2 pathway promotes gastric cancer progression and metastasis Oncogene. 2021 May;40(20):3610-3623._x000D_ 3: Garmendia I, Redin E, Montuenga LM, Calvo A. YES1: A Novel Therapeutic Target and Biomarker in Cancer Mol Cancer Ther. 2022 Sep 6;21(9):1371-1380._x000D_ 4: Mascharak S, desJardins-Park HE, Davitt MF, Griffin M, Borrelli MR, Moore AL, Chen K, Duoto B, Chinta M, Foster DS, Shen AH, Januszyk M, Kwon SH, Wernig G, Wan DC, Lorenz HP, Gurtner GC, Longaker MT. Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring Science. 2021 Apr 23;372(6540):eaba2374._x000D_ 5: Pang Y, Liu Z, Han H, Wang B, Li W, Mao C, Liu S. Peptide SMIM30 promotes HCC development by inducing SRC/YES1 membrane anchoring and MAPK pathway activation J Hepatol. 2020 Nov;73(5):1155-1169._x000D_ 6: Zhou W, Liu K, Zeng L, He J, Gao X, Gu X, Chen X, Jing Li J, Wang M, Wu D, Cai Z, Claesson-Welsh L, Ju R, Wang J, Zhang F, Chen Y. Targeting VEGF-A/VEGFR2 Y949 Signaling-Mediated Vascular Permeability Alleviates Hypoxic Pulmonary Hypertension Circulation. 2022 Dec 13;146(24):1855-1881._x000D_ 7: Pan J, Liu F, Xiao X, Xu R, Dai L, Zhu M, Xu H, Xu Y, Zhao A, Zhou W, Dang Y, Ji G. METTL3 promotes colorectal carcinoma progression by regulating the m6A-CRB3-Hippo axis J Exp Clin Cancer Res. 2022 Jan 10;41(1):19._x000D_ 8: Fan H, Wang X, Li W, Shen M, Wei Y, Zheng H, Kang Y. ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP Genes Dev. 2020 Oct 1;34(19-20):1359-1372._x000D_ 9: Hamanaka N, Nakanishi Y, Mizuno T, Horiguchi-Takei K, Akiyama N, Tanimura H, Hasegawa M, Satoh Y, Tachibana Y, Fujii T, Sakata K, Ogasawara K, Ebiike H, Koyano H, Sato H, Ishii N, Mio T. YES1 Is a Targetable Oncogene in Cancers Harboring YES1 Gene Amplification Cancer Res. 2019 Nov 15;79(22):5734-5745._x000D_ 10: Cai X, Chen Y, Man D, Yang B, Feng X, Zhang D, Chen J, Wu J. RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner Cell Death Discov. 2021 Oct 27;7(1):315. _x000D_ _x000D_ Products Related to YES1 Active Human can be found at Proteins

• Short Description:

  Catalog Number: B2013749 (10 ug)

• Weight:

  0.8

• Length:

  2

• Width:

  0.9

• Height:

  0.9

• Height :

  0.9