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Aloenin

CAT: 0804-HY-N0495-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0495-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aloenin (Aloenin A) is a kind of natural product, has effective clearing and free radical activity, and has moderate inhibitory activity on β-secretion (BACE) (IC50=14.95 μg/mL) . Aloenin suppresses peritoneal hypertrophy in large rats and suppresses its release[1][2][3][4].
CAS Number
38412-46-3
Product Name Alternative
Aloenin A
UNSPSC
12352005
Target
Beta-secretase
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aloenin.html
Purity
99.91
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=C(C(O3)=CC(OC)=CC3=O)C(C)=CC(O)=C2
Molecular Formula
C19H22O10
Molecular Weight
410.37
References & Citations
[1]Sun YN, et al. Antioxidant and anti-osteoporotic effects of anthraquinones and related constituents from the aqueous dissolved Aloe exudates. Nat Prod Res. 2017 Dec;31 (23) :2810-2813.|[2]Gao B, et al. Active constituents from Aloe arborescens as BACE inhibitors. Yao Xue Xue Bao. 2006 Oct;41 (10) :1000-3.|[3]Nakagomi K, et al. Inhibition by aloenin and barbaloin of histamine release from rat peritoneal mast cells[J]. Agricultural and biological chemistry, 1987, 51 (6) : 1723-1724.|[4]Deora N, et al. Lipase activity inhibited by aloenin A: Glycoside from Aloe vera (L.) Burm. f.-In vitro and molecular docking studies. J Mol Recognit. 2023 Feb;36 (2) :e3002.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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