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Recombinant Human Alpha Crystallin A

CAT: 0014-11075P-20-1Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0014-11075P-20-1Size:20 µg
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Description
Recombinant Human Alpha Crystallin A
CAS Number
9000-83-3
Product Name Alternative
CRYAA
UniProt
P02489
Reactivity
Human
Target Antigen
Alpha Crystallin A
Target
Alpha Crystallin A
Type
Protein
Applications
WB
Concentration
Lot Specific
Dilution
Dilute in PBS or medium that is identical to that used in the assay system.
Form
Liquid
Buffer
20 mM Tris
Storage Conditions
Store at 4°C if entire vial will be used within 2-4 weeks. Store at or below -20°C for longer periods of time. For long term storage, addition of a carrier protein (0.1% HSA or BSA) is recommended.
Specificity
Alpha Crystallin A
Formulation
Sterile-filtered colorless solution contains 20mM Tris-HCl, pH 7.5, 50mM NaCl and 1mM EDTA.
Buffer pH
pH 7.5
Target Background
Alpha crystallins are composed of two gene products: alpha-A (acidic) and alpha-B (basic). Alpha crystallins are induced by heat shock and are members of the small heat shock protein family. They act as molecular chaperones. In addition, alpha crystallins have autokinase activity and play a role in intracellular architecture. The expression of alpha crystalline A is preferentially restricted to lens cells.

UniProtKB · P02489

Alpha-crystallin A chain

CRYAA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02489
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CRYAA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A140G945, E9PHE4, Q53X53
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationDisulfide bondGlycoproteinOxidationPhosphoprotein

Disease

CataractDisease variant

Molecular function

ChaperoneEye lens protein

Cellular component

CytoplasmNucleus

Ligand

Metal-bindingZinc

Biological process

Sensory transductionVision

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