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IL-37, Human

CAT: 0804-HY-P70455-01Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-P70455-01Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. IL-37 Protein, Human is the recombinant human-derived IL-37 protein, expressed by E. coli , with tag free.
Product Name Alternative
IL-37 Protein, Human, Human, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/il-37-protein-human.html
Purity
97.04
Smiles
KNLNPKKFSIHDQDHKVLVLDSGNLIAVPDKNYIRPEIFFALASSLSSASAEKGSPILLGVSKGEFCLYCDKDKGQSHPSLQLKKEKLMKLAAQKESARRPFIFYRAQVGSWNMLESAAHPGWFICTSCNCNEPVGVTDKFENRKHIEFSFQPVCKAEMSPSEVSD
Molecular Formula
27178 (Gene_ID) Q9NZH6-1 (K53-D218) (Accession)
Molecular Weight
Approximately 18-20 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
[1]Lijuan Wang, et al. Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy. Oncol Lett. 2018 Apr;15 (4) :4711-4719.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins

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