IL-37, Human

• UNSPSC Description:

  IL-37 protein is an important immunoregulatory cytokine that suppresses innate inflammation and immune responses and reduces excessive inflammation. It signals intracellularly through nuclear translocation of SMAD3 and extracellularly through binding to its receptors, consisting of IL18R1 and IL18RAP. IL-37 Protein, Human is the recombinant human-derived IL-37 protein, expressed by E. coli , with tag free.

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/il-37-protein-human.html

• Purity:

  97.04

• Smiles:

  KNLNPKKFSI HDQDHKVLVL DSGNLIAVPD KNYIRPEIFF ALASSLSSAS AEKGSPILLG VSKGEFCLYC DKDKGQSHPS LQLKKEKLMK LAAQKESARR PFIFYRAQVG SWNMLESAAH PGWFICTSCN CNEPVGVTDK FENRKHIEFS FQPVCKAEMS PSEVSD

• Molecular Weight:

  Approximately 18-20 kDa

• References & Citations:

  [1]Lijuan Wang, et al. Interleukin-37: A crucial cytokine with multiple roles in disease and potentially clinical therapy. Oncol Lett. 2018 Apr;15(4):4711-4719.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stored at -20°C for 2 years