LL-37, human

• Description:

  LL-37, human is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human could help protect the cornea from infection and modulates wound healing[1][2][3].

• UNSPSC:

  12352209

• Target:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/ll-37-human.html

• Purity:

  99.60

• Solubility:

  H2O : 50 mg/mL (ultrasonic)

• Smiles:

  O=C (N[C@@H] (CC (C) C) C (NCC (N[C@@H] (CC (O) =O) C (N[C@@H] (CC1=CC=CC=C1) C (N[C@@H] (CC2=CC=CC=C2) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CCCCN) C (N[C@@H] (CO) C (N[C@@H] (CCCCN) C (N[C@@H] (CCC (O) =O) C (N[C@@H] (CCCCN) C (N[C@@H] ([C@@H] (C) CC) C (NCC (N[C@@H] (CCCCN) C (N[C@@H] (CCC (O) =O) C (N[C@@H] (CC3=CC=CC=C3) C (N[C@@H] (CCCCN) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H] (C (C) C) C (N[C@@H] (CCC (N) =O) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] ([C@@H] (C) CC) C (N[C@@H] (CCCCN) C (N[C@@H] (CC (O) =O) C (N[C@@H] (CC4=CC=CC=C4) C (N[C@@H] (CC (C) C) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CC (N) =O) C (N[C@@H] (CC (C) C) C (N[C@@H] (C (C) C) C (N5[C@@H] (CCC5) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] ([C@H] (O) C) C (N[C@@H] (CCC (O) =O) C (N[C@@H] (CO) C (O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) [C@H] (CC (C) C) N

• Molecular Formula:

  C205H340N60O53

• Molecular Weight:

  4493.26

• References & Citations:

  [1]Dürr UH, et al. LL-37, the only human member of the cathelicidin family of antimicrobial peptides. Biochim Biophys Acta. 2006 Sep;1758 (9) :1408-25.|[2]Huang LC, et al. Multifunctional roles of human cathelicidin (LL-37) at the ocular surface. Invest Ophthalmol Vis Sci. 2006 Jun;47 (6) :2369-80.|[3]Hou M, et al. Antimicrobial peptide LL-37 and IDR-1 ameliorate MRSA pneumonia in vivo. Cell Physiol Biochem. 2013;32 (3) :614-23.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• Citation 01:

  ACS Omega. 2025 Aug 12;10 (33) :36994-37003.|Commun Biol. 2022 Jun 8;5 (1) :559.|FASEB J. 2025 Oct 31;39 (20) :e71164.|Int Immunopharmacol. 2024 Mar 10:129:111636.

• CAS Number:

  154947-66-7