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Imazalil (Standard)

CAT: 0804-HY-B1134R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1134R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Imazalil (Standard) is the analytical standard of Imazalil. This product is intended for research and analytical applications. Imazalil (Enilconazole) is a fungicide. Imazalil has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil is commonly used to protect various agricultural crops against fungal attack. Imazalil induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder[1][2][3].
CAS Number
35554-44-0
Product Name Alternative
Enilconazole (Standard)
UNSPSC
12352005
Target
Fungal; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/imazalil-standard.html
Smiles
C=CCOC(C1=CC=C(Cl)C=C1Cl)CN2C=CN=C2
Molecular Formula
C14H14Cl2N2O
Molecular Weight
297.18
References & Citations
[1]Hiroyuki Kojima, et al. Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ. Toxicol Appl Pharmacol. 2012 Mar 15;259 (3) :338-45.|[2]Shohei Yoshimaru, et al. Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR. J Toxicol Sci. 2018;43 (7) :443-450.|[3]Cuiyuan Jin, et al. Chronic exposure of mice to low doses of imazalil induces hepatotoxicity at the physiological, biochemical, and transcriptomic levels. Environ Toxicol. 2018 Jun;33 (6) :650-658.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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