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Leuhistin

CAT: 0804-HY-116126Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116126Size:1 Each
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Description
Leuhistin is an AP-M (aminopeptidase-M) inhibitor. AP-M is an inactivating enzyme of bioactive peptides in cerebral membranes. Leuhistin can be produced by Bacillus laterosporus BMI156-14F1[1].
CAS Number
129085-76-3
UNSPSC
12352005
Target
Aminopeptidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/leuhistin.html
Smiles
O=C(O)[C@](CC1=CNC=N1)(O)[C@@H](N)CC(C)C
Molecular Formula
C11H19N3O3
Molecular Weight
241.29
References & Citations
[1]Aoyagi T, et al. Leuhistin, a new inhibitor of aminopeptidase M, produced by Bacillus laterosporus BMI156-14F1. I. Taxonomy, production, isolation, physico-chemical properties and biological activities. J Antibiot (Tokyo) . 1991 Jun;44 (6) :573-8.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Leuhistin

Leuhistin is an organonitrogen compound and an organooxygen compound. It is functionally related to a beta-amino acid.

CAS Number129085-76-3
PubChem CID131057
IUPAC Name(2R,3S)-3-amino-2-hydroxy-2-(1H-imidazol-5-ylmethyl)-5-methylhexanoic acid
Molecular FormulaC11H19N3O3
Molecular Weight241.29
XLogP-2.3
Topological Polar Surface Area112
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count17
Formal Charge0
Complexity273
SMILES
CC(C)C[C@@H]([C@](CC1=CN=CN1)(C(=O)O)O)N
InChI
InChI=1S/C11H19N3O3/c1-7(2)3-9(12)11(17,10(15)16)4-8-5-13-6-14-8/h5-7,9,17H,3-4,12H2,1-2H3,(H,13,14)(H,15,16)/t9-,11+/m0/s1
InChIKey
WZFDNGAENBEYMA-GXSJLCMTSA-N
Chemical Structure
2D Structure
2D structure of Leuhistin
CAS: 129085-76-3
CID: 131057
Formula: C11H19N3O3
MW: 241.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight241.29
XLogP3-2.3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass241.14264148
Monoisotopic Mass241.14264148
Topological Polar Surface Area112 Ų
Heavy Atom Count17
Formal Charge0
Complexity273
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19199000-01Leuhistin

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