Products for Research Use Only
RegisterLogin

Cyclooctyne-O-PFP ester

CAT: 0804-HY-126518-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-126518-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cyclooctyne-O-PFP ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. Cyclooctyne-O-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
886209-60-5
UNSPSC
12352203
Hazard Statement
H302-H315-H319-H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cyclooctyne-o-pfp-ester.html
Purity
95.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)COC2C#CCCCCC2
Molecular Formula
C16H13F5O3
Molecular Weight
348.27
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Sun, Ying, et al. Anti-PSMA Antibodies Conjugated to Nuclear Receptor Ligand Polypeptides. 20150152187A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker

Related Products

CatalogName
HY-133576Cyclooctyne-O-amido-PEG4-PFP ester
HY-133573Cyclooctyne-O-amido-PEG2-PFP ester
HY-133575Cyclooctyne-O-amido-PEG3-PFP ester
HY-126517-01Cyclooctyne-O-NHS ester
HY-138467-01Mal-PFP ester
HY-119343-01Biotin-PFP ester
HY-132097Bromo-PEG4-PFP ester
HY-138333Azido-PEG7-PFP ester
HY-141256Bis-PEG13-PFP ester
HY-126998-01Bis-PEG4-PFP ester

Alternative Products

CatalogName
MBS5770609Cyclooctyne-O-PFP ester
MBS5799996Cyclooctyne-O-amido-PEG3-PFP ester
MBS5799999Cyclooctyne-O-amido-PEG2-PFP ester
GTR19234433-01Cyclooctyne-O-amido-PEG4-PFP ester
MBS5771884Cyclooctyne-O-NHS ester
T14612-01Biotin-PFP ester
T38798Mal-PFP ester
abx181383-01(+)-Biotin-PFP-ester
sc-475997(+) -Biotin-PFP-ester

Popular Products