(R)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline

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804-HY-168348

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UNSPSC Description: (R)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline is a linker for NX-2127 (HY-153220A)[1].
Target Antigen: PROTAC Linkers
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/r-4-1-pyrrolidin-3-ylmethyl-piperidin-4-yl-aniline.html
Smiles: NC(C=C1)=CC=C1C(CC2)CCN2C[C@H]3CNCC3
Molecular Weight: 259.39
References & Citations: [1]Robbins D W, et al. Discovery and preclinical pharmacology of NX-2127, an orally bioavailable degrader of Bruton’s tyrosine kinase with immunomodulatory activity for the treatment of patients with B cell malignancies[J]. Journal of Medicinal Chemistry, 2024, 67(4): 2321-2336.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-168348	(R)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline
HY-168303	(S)-4-(1-(Pyrrolidin-3-ylmethyl)piperidin-4-yl)aniline
HY-169975	tert-Butyl 4-(4-(piperazin-1-ylmethyl)piperidin-1-yl)benzoate
HY-168238	(4-(3-Bromobenzyl)piperazin-1-yl)(piperidin-4-yl)methanone
HY-49395A-05	(S)-4-(4-((4-(4-((2,6-Dioxopiperidin-3-yl)carbamoyl)-3-fluorophenyl)piperazin-1-yl)methyl)piperidin-1-yl)benzoic acid hydrochloride
HY-49395A-03	(S)-4-(4-((4-(4-((2,6-Dioxopiperidin-3-yl)carbamoyl)-3-fluorophenyl)piperazin-1-yl)methyl)piperidin-1-yl)benzoic acid hydrochloride
HY-49395A-04	(S)-4-(4-((4-(4-((2,6-Dioxopiperidin-3-yl)carbamoyl)-3-fluorophenyl)piperazin-1-yl)methyl)piperidin-1-yl)benzoic acid hydrochloride
HY-49395A-02	(S)-4-(4-((4-(4-((2,6-Dioxopiperidin-3-yl)carbamoyl)-3-fluorophenyl)piperazin-1-yl)methyl)piperidin-1-yl)benzoic acid hydrochloride
HY-49395A-01	(S)-4-(4-((4-(4-((2,6-Dioxopiperidin-3-yl)carbamoyl)-3-fluorophenyl)piperazin-1-yl)methyl)piperidin-1-yl)benzoic acid hydrochloride
HY-168309	7-(Piperidin-4-ylmethyl)-2,7-diazaspiro[3.5]nonane

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