DB07268

• Description:

  DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319

• Target:

  JNK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/DB07268.html

• Concentration:

  10mM

• Purity:

  99.49

• Solubility:

  DMSO : ≥ 32 mg/mL

• Smiles:

  O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2

• Molecular Formula:

  C17H15N5O2

• Molecular Weight:

  321.33

• Precautions:

  H302, H315, H319

• References & Citations:

  [1]Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17 (3) :668-72.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  JNK1

• CAS Number:

  [929007-72-7]