DB07268

• Description :

  DB07268 is a potent and selective JNK1 inhibitor with an IC50 value of 9 nM.

• CAS Number :

  [929007-72-7]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319

• Target :

  JNK

• Type :

  Reference compound

• Related Pathways :

  MAPK/ERK Pathway

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/DB07268.html

• Concentration :

  10mM

• Purity :

  99.49

• Solubility :

  DMSO : ≥ 32 mg/mL

• Smiles :

  O=C(N)C1=CC=CC=C1NC2=NC(NC3=CC=CC(O)=C3)=NC=C2

• Molecular Formula :

  C17H15N5O2

• Molecular Weight :

  321.33

• Precautions :

  H302, H315, H319

• References & Citations :

  [1]Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17 (3) :668-72.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  JNK1