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Dexelvucitabine

CAT: 0804-HY-14920-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14920-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dexelvucitabine (Reverset; d-d4FC), a Cytidine analog, is an orally active nucleoside reverse transcriptase inhibitor. Dexelvucitabine is a powerful agent against HIV-1-resistant viruses containing a thymidine analog and/or M184V mutation in the viral polymerase. Dexelvucitabine is a 2′-Deoxycytidine antiretroviral agent[1].
CAS Number
134379-77-4
Product Name Alternative
Reverset; d-d4FC
UNSPSC
12352005
Hazard Statement
H315-H319
Target
HIV; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dexelvucitabine.html
Concentration
10mM
Purity
99.52
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1N(C=C(C(N)=N1)F)[C@]2([H])O[C@@H](C=C2)CO
Molecular Formula
C9H10FN3O3
Molecular Weight
227.19
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Brenda I Hernandez-Santiago, et al. Antiviral and cellular metabolism interactions between Dexelvucitabine and lamivudine. Antimicrob Agents Chemother. 2007 Jun;51 (6) :2130-5.|[2]L Ma, et al. Pharmacokinetics of the antiviral agent beta-D-2',3'-didehydro-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys. Antimicrob Agents Chemother. 1999 Feb;43 (2) :381-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
HIV-1

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CatalogName
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