Products for Research Use Only
RegisterLogin

ICR-191 dihydrochloride

CAT: 0013-GTR19320109-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19320109-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ICR-191 enhances the binding of Cisplatin to DNA and increases cell sensitivity to Cisplatin. It significantly elevates the expression of phosphorylated H2AX (γH2AX), particularly in cells undergoing DNA replication, and is applicable in leukemia research.
CAS Number
17070-45-0
Molecular Weight
451.21
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Icr 191

Icr 191 appears as yellow crystalline or chunky solid. (NTP, 1992)

CAS Number17070-45-0
PubChem CID54606642
IUPAC NameN-(2-chloroethyl)-N'-(6-chloro-2-methoxyacridin-9-yl)propane-1,3-diamine;hydrochloride
Molecular FormulaC19H22Cl3N3O
Molecular Weight414.8
Topological Polar Surface Area46.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Heavy Atom Count26
Formal Charge0
Complexity401
SMILES
COC1=CC2=C(C3=C(C=C(C=C3)Cl)N=C2C=C1)NCCCNCCCl.Cl
InChI
InChI=1S/C19H21Cl2N3O.ClH/c1-25-14-4-6-17-16(12-14)19(23-9-2-8-22-10-7-20)15-5-3-13(21)11-18(15)24-17;/h3-6,11-12,22H,2,7-10H2,1H3,(H,23,24);1H
InChIKey
PQVLERLLNMDETJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Icr 191
CAS: 17070-45-0
CID: 54606642
Formula: C19H22Cl3N3O
MW: 414.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight414.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Exact Mass413.082845
Monoisotopic Mass413.082845
Topological Polar Surface Area46.2 Ų
Heavy Atom Count26
Formal Charge0
Complexity401
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19241864-01ICR-340 dihydrochloride
GTR19194319ICR 283
GTR19258415-01R1-ICR-5
GTR19173987-01ML-191
GTR19167524-01I-191
GTR19154745-01ML-191
GTR19157367-01I-191
GTR19202681-01KX-01-191
GTR19262006-01Antibacterial agent 191
GTR19261940-01Anticancer agent 191

Alternative Products

CatalogName
HY-W414334ICR-191 (dihydrochloride)
T202670-01ICR-340 dihydrochloride
TRC-A190920-2.5MGAcridine Mutagen ICR 191
B4915-10BAZ2-ICR
T32135ICR 283

Popular Products