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Rabbit Human plasminogen Antibody

CAT: 0013-GTR17701467Size: 1 mLDry Ice: NoHazardous: No
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CAT#:0013-GTR17701467Size:1 mL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal to Plasminogen
UniProt
P00747
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Source
Native plasminogen is a single polypeptide chain, synthesized in the liver. Its molecular weight has been reported to be 81,000 and 92,000. Part of the molecule contains the active serine esterase of plasmin. On activation it is converted to two polypeptide chains linked by disulphide bridges. Three different abnormal molecular forms of plasminogen have been described. Normal adult plasma contains 10-20 mg/100 ml plasminogen. Different congenital molecular structure abnormalities associated with recurrent thrombosis have been described, but are extremely rare. In liver disease plasminogen activity may be reduced. Freund’s complete adjuvant is used in the first step of the immunization procedure.
Form
Deplipidated, heat inactivated, lyophilized, stable whole serum. No preservative added. Total protein and IgG concentrations in the antiserum are comparable to those of pooled normal rabbit serum. No foreign proteins added.
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Host or Source
Rabbit

UniProtKB · P00747

Plasminogen

PLMN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P00747
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PLG
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q15146, Q5TEH4, Q6PA00
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Blood coagulationFibrinolysisHemostasisTissue remodeling

PTM

Cleavage on pair of basic residuesDisulfide bondGlycoproteinPhosphoproteinZymogen

Disease

Disease variantThrombophilia

Molecular function

HydrolaseProteaseSerine protease

Domain

KringleRepeatSignal

Cellular component

Secreted

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