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Metoprolol

CAT: 0804-HY-17503-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17503-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Metoprolol is an orally active, selective β1-adrenoceptor antagonist. Metoprolol shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3].
CAS Number
51384-51-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Adrenergic Receptor; Apoptosis
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Infection; Endocrinology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Metoprolol.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(CNC(C)C)COC1=CC=C(CCOC)C=C1
Molecular Formula
C15H25NO3
Molecular Weight
267.36
Precautions
H302, H315, H319, H335
References & Citations
[1]Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.|[2]Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547 (2) :195-201.|[3]Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10 (4) : 124-129.|[4]Su Q, et al. Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats. Exp Clin Cardiol. 2013 Spring;18 (2) :161-5.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor
Citation 01
Biochem Biophys Res Commun. 2025 Oct 30:786:152756.|Chemosphere. 2019 Jun:225:378-387.|Clin Pharmacol Ther. 2024 Feb;115 (2) :309-317.|Environ Toxicol. 2024 Mar;39 (3) :1682-1699.|Int Immunopharmacol. 2024 Aug 9:140:112894.|J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jul 1:1227:123804.|J Intern Med. 2024 Sep;296 (3) :291-297.|J Pharm Biomed Anal. 2021 Feb 20:195:113870.|Preprints. 2023 Jun 19.|SSRN. 2024 May 30.|bioRxiv. 2024 Mar 29.|PLoS One. 2024 Aug 14;19 (8) :e0301875.|Eur J Med Chem. 2024 Dec 5:279:116842.|iScience. 2025 Jan 17;28 (2) :111831.|J Pharmacol Sci. 2020 Sep;144 (1) :30-42.

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