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D-Mannosamine (hydrochloride)

CAT: 0804-HY-W021425-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W021425-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D-Mannosamine ((2S,3R,4S,5R) -2-Amino-3,4,5,6-tetrahydroxyhexanal) hydrochloride is a six-carbon amino sugar and an amino derivative of D-mannose. D-Mannosamine hydrochloride can block mannose receptors[1].
CAS Number
5505-63-5
Product Name Alternative
(2S,3R,4S,5R) -2-Amino-3,4,5,6-tetrahydroxyhexanal (hydrochloride)
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/2s-3r-4s-5r-2-amino-3-4-5-6-tetrahydroxyhexanal-hydrochloride.html
Purity
98.0
Solubility
DMSO : 25 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C[C@@H](N)[C@H]([C@@H]([C@@H](CO)O)O)O.[H]Cl
Molecular Formula
C6H14ClNO5
Molecular Weight
215.63
Precautions
H302, H315, H319, H335
References & Citations
[1]Yi J, et al. Chitosan and mannose-modified dual-functional mRNA-LNP vaccines for robust systemic and mucosal immune responses. J Control Release. 2025 Aug 10;384:113891.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

D-Mannose, 2-amino-2-deoxy-, hydrochloride (1:1)
CAS Number5505-63-5
PubChem CID9899264
IUPAC Name(2S,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal;hydrochloride
Molecular FormulaC6H14ClNO5
Molecular Weight215.63
Topological Polar Surface Area124
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count13
Formal Charge0
Complexity142
SMILES
C([C@H]([C@H]([C@@H]([C@@H](C=O)N)O)O)O)O.Cl
InChI
InChI=1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4-,5-,6-;/m1./s1
InChIKey
CBOJBBMQJBVCMW-MVNLRXSJSA-N
Chemical Structure
2D Structure
2D structure of D-Mannose, 2-amino-2-deoxy-, hydrochloride (1:1)
CAS: 5505-63-5
CID: 9899264
Formula: C6H14ClNO5
MW: 215.63
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight215.63
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass215.0560502
Monoisotopic Mass215.0560502
Topological Polar Surface Area124 Ų
Heavy Atom Count13
Formal Charge0
Complexity142
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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