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4A3-SC10

CAT: 0013-GTR19277679-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277679-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) utilized in the formation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. In mice, these LNPs, which contain 4A3-SC10, preferentially accumulate in the liver, kidney, and spleen. Furthermore, LNPs with 4A3-SC10 that encapsulate an mRNA reporter stimulate reporter expression in 4T1 breast cancer cells, B16/F10 melanoma cells, and AML12 hepatocytes.
Storage Conditions
-20°C
Notes
For research use only.

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