Products for Research Use Only

Bleximenib

CAT: 0013-GTR19277529-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277529-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bleximenib (JNJ-75276617) oxalate is an orally active and highly selective menin–KMT2A interaction inhibitor, with IC50 values of 0.1 nM in humans, 0.045 nM in mice, and ≤0.066 nM in dogs, Bleximenib effectively suppresses tumor cell proliferation while inducing apoptosis and cellular differentiation. Bleximenib serves as a powerful investigational agent for leukemia and other KMT2A-driven malignancies in preclinical cancer research.
CAS Number
2654081-35-1
Smiles
[C@@H] (CCCN (CCOC) C) (C (C) C) N1CC2 (CN (CC2) C=3C (OC4=C (C (N (C (C) C) CC) =O) C=C (F) C=C4) =NN=CN3) C1
Molecular Formula
C32H50FN7O3
Molecular Weight
599.8
Storage Conditions
-20°C
Notes
For research use only.