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BB-Cl-Yne

CAT: 0013-GTR19277397-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277397-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BB-Cl-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-CL-Yne inhibits PAD1-4 with Kinact/KI values of 6,400, 3,600, 10,800, and 4,900 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.
CAS Number
2219324-71-5
Smiles
[C@H] (NC (=O) C1=CC=C (C=C1) C2=CC=C (C#C) C=C2) (CCCNC (CCl) =N) C=3NC=4C (N3) =CC=CC4
Molecular Formula
C28H26ClN5O
Molecular Weight
483.99
Storage Conditions
-20°C
Notes
For research use only.

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