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Merbarone

CAT: 0013-GTR19277371-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277371-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Merbarone is a Type II DNA topoisomerase inhibitor that suppresses the catalytic activity of human topoisomerase IIα by blocking DNA cleavage, subsequently inducing activation of caspase-activated DNase and excision of chromosomal DNA loops from the nuclear matrix, Merbarone triggers apoptosis in CEM cells through activation of ICE/CED-3-like proteases, making it a mechanistically informative compound for studying DNA damage responses and apoptosis pathways.
CAS Number
97534-21-9
Purity
99.51% (May vary between batches)
Smiles
O=C (NC=1C=CC=CC1) C2C (=O) NC (=S) NC2=O
Molecular Formula
C11H9N3O3S
Molecular Weight
263.27
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
C01860-5mgMerbarone
HY-19024RMerbarone (Standard)

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