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TNG961

CAT: 0013-GTR19277322-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19277322-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TNG961 is a potent, highly selective, CRBN-dependent HBS1L (GSPT3) molecular chaperone inhibitor. By degrading HBS1L, TNG961 specifically disrupts protein homeostasis in FOCAD-deficient cancer cells, thereby inducing growth inhibition and cell death. TNG961 can be used in studies of FOCAD-deficient tumors.
Smiles
O=C ([C@H] (CC1) C2=CC3=CC=CC (NC (NC (C) (C) C4=CC5=C (C=C (C (F) (F) F) C=C5) S4) =O) =C3C=C2) NC1=O
Molecular Formula
C28H24F3N3O3S
Molecular Weight
539.57
Storage Conditions
-20°C
Notes
For research use only.

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