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Methoxycoronarin D

CAT: 0804-HY-N3632Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N3632Size:1 Each
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Description
Methoxycoronarin D can be isolated from Hedychium coronarium J. Koenig and is a potent inhibitor of NF-κB with an IC50 value of 7.3 μM. Methoxycoronarin D is also a selective inhibitor of COX-1 with an IC50 value of 0.9 μM[1].
CAS Number
157528-81-9
Product Name Alternative
Coronarin D Me ether
UNSPSC
12352005
Target
COX; NF-κB
Type
Natural Products
Related Pathways
Immunology/Inflammation; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/methoxycoronarin-d.html
Solubility
10 mM in DMSO
Smiles
C[C@]12CCCC(C)(C)[C@@H]1CCC([C@@H]2C/C=C3CC(OC)OC\3=O)=C
Molecular Formula
C21H32O3
Molecular Weight
332.48
References & Citations
[1]Endringer D C, et al. Cancer chemoprevention activity of labdane diterpenes from rhizomes of Hedychium coronarium[J]. Revista Brasileira de Farmacognosia, 2014, 24: 408-412.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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