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AP232 dihydrochloride

CAT: 0013-GTR19274973-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274973-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AP232 dihydrochloride is a selective U2AF1-UHM inhibitor with an IC50 value of 7.96 μM. It exhibits 2.8-24 times selectivity over other UHM-containing proteins and demonstrates anti-leukemic activity, showing heightened effectiveness in cell lines with splice factor mutations. AP232 dihydrochloride can induce G2/M and G1 phase arrest in leukemia cells, impair lysosomal acidification, and inhibit autophagy (autophagy) . This compound is applicable in cancer research, specifically for leukemia.
Storage Conditions
-20°C
Notes
For research use only.

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