Products for Research Use Only

AP232

CAT: 0013-GTR19273270-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273270-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AP232 is a selective inhibitor of U2AF1-UHM with an IC50 value of 7.96 μM. It shows 2.8 to 24 times selectivity over other UHM-containing proteins. AP232 exhibits anti-leukemia activity and demonstrates heightened effectiveness in cell lines with splicing factor mutations. It can induce G2/M and G1 phase arrest in leukemia cells, impair lysosomal acidification, and inhibit autophagy (autophagy) . AP232 is applicable in cancer research, particularly for leukemia studies.
Storage Conditions
-20°C
Notes
For research use only.

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