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PAV-174

CAT: 0013-GTR19274870-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274870-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PAV-174 is a potent antiviral agent targeting host proteins, capable of preventing HSV-1 infection in cell and human brain organoid models (with an IC50 of 0.02 μM in Vero cells) . It effectively inhibits tau protein phosphorylation induced by oxidized macrophage migration inhibitory factor (oxMIF) both in vitro and in vivo, independent of viral infection. PAV-174 reduces tau phosphorylation due to HSV-1 infection via the Akt/GSK3β signaling pathway and is applicable for research related to Alzheimer's disease.
Storage Conditions
-20°C
Notes
For research use only.

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