XH-30

CAT: 0013-GTR19274727-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19274727-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

XH-30 is a potent, selective, and orally active PKMYT1 inhibitor with an IC50 of 4.1 nM. It suppresses the proliferation of P53-mutated triple-negative breast cancer (TNBC) cells by inducing G2/M phase release, DNA damage, and apoptosis. In the MDA-MB-231 mouse model, XH-30 demonstrates antitumor activity and can be used in studies of P53-mutated TNBC.

CAS Number

3077136-87-6

Smiles

O=C (N) C=1C=C2N=C (OC2=C (C1N) C3=C (C=CC (O) =C3C) C) C4CC4

Molecular Formula

C19H19N3O3

Molecular Weight

337.38

Storage Conditions

-20°C

Notes

For research use only.

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