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β-Funaltrexamine

CAT: 0013-GTR19274705-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274705-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
β-Funaltrexamine (β-FNA) is a selective, irreversible antagonist of the μ opioid receptor (μopioid receptor) with anti-inflammatory and neuroprotective properties. It reduces TLR4 signaling, inhibits cytokine-induced iNOS activation and neuroinflammation, and improves neuronal degeneration. Additionally, β-Funaltrexamine suppresses NF-κB signaling and chemokine expression in human astrocytes and mice. This compound is utilized in research for neurodegenerative diseases, such as stroke.
CAS Number
72782-05-9
Smiles
O[C@]12[C@@]34C=5C (O[C@]3 ([C@H] (NC (/C=C/C (OC) =O) =O) CC1) [H]) =C (O) C=CC5C[C@]2 (N (CC6CC6) CC4) [H]
Molecular Formula
C25H30N2O6
Molecular Weight
454.52
Storage Conditions
-20°C
Notes
For research use only.

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