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CXCR2-IN-3

CAT: 0013-GTR19274548-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274548-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CXCR2-IN-3 is a CXCR2 inhibitor with an IC50 of 11.37 μM. It inhibits the CXCR2-Ca2+ signaling pathway, thereby blocking autophagic flux and promoting ROS-mediated apoptosis. Additionally, CXCR2-IN-3 suppresses the CXCR2-NLRP3 canonical pathway, reducing the expression of tumor-promoting markers. This compound induces autophagy-dependent cell death in polyploid giant cancer cells (PGCC) and is applicable in studies related to oral squamous cell carcinoma (OSCC) .
Storage Conditions
-20°C
Notes
For research use only.

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