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LY456236 free base

CAT: 0013-GTR19275079-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19275079-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY456236 free base is a selective, non-competitive, orally active antagonist of the glutamate receptor 1 (mGlu1), effectively inhibiting phosphoinositide hydrolysis with an IC50 of 0.145 μM. Additionally, it inhibits EGFR with an IC50 of 0.918 μM. By suppressing the MAPK pathway, LY456236 free base blocks cell proliferation and counters the anti-apoptotic effects of DHPG. This compound is useful for seizure research.
CAS Number
338738-57-1
Smiles
N=1C=NC (NC2=CC=C (OC) C=C2) =C3C=C (OC) C=CC13
Molecular Formula
C16H15N3O2
Molecular Weight
281.32
Storage Conditions
-20°C
Notes
For research use only.

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