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LY3295668 erbumine

CAT: 0013-GTR19274902-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274902-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LY3295668 (AK-01) erbumine is a highly selective, orally active inhibitor of Aurora-A kinase, with Ki values of 0.8 nM for AurA and 1038 nM for AurB. It effectively suppresses AurA autophosphorylation, inducing mitotic arrest and apoptosis (apoptosis), while preventing polyploidy associated with AurB inhibition. LY3295668 erbumine is applicable for studying small cell lung cancer.
CAS Number
1919888-07-5
Smiles
C (C) (C) (C) N.C ([C@]1 (C (O) =O) C[C@@H] (C) N (CC2=C (F) C (Cl) =CC=C2) CC1) C=3N=C (NC4=NNC (C) =C4) C=CC3F
Molecular Formula
C28H37ClF2N6O2
Molecular Weight
563.09
Storage Conditions
-20°C
Notes
For research use only.

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